The register
The register lists Substrate Bio Ltd in London as a licensed sponsor on Global Business Mobility: Senior or Specialist Worker and Skilled Worker, 2 routes in all, and has done since at least 2026. Rating on the current register: Worker (A rating).
Companies House lists the business as Substrate Bio Ltd, company number 17191596, a private limited company. The registered office is at 71-75 Shelton Street, Covent Garden, London, WC2H 9JQ, WC2H 9JQ. Its filed activity puts it in it, software and media.
Holding a licence is the expensive, slow part done. For Substrate Bio Ltd the question each time is only whether the role and the pay fit the current rules, and that is checked per vacancy.